Propofol Infusion Syndrome:Rare, but Lethal. Do Not Overlook It

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Propofol infusion rate does not affect local pain on injection.

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Propofol infusion syndrome.

The clinical features of propofol infusion syndrome (PRIS) are acute refractory bradycardia leading to asystole, in the presence of one or more of the following: metabolic acidosis (base deficit > 10 mmol.l(-1)), rhabdomyolysis, hyperlipidaemia, and enlarged or fatty liver. There is an association between PRIS and propofol infusions at doses higher than 4 mg.kg(-1).h(-1) for greater than 48 h d...

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ژورنال

عنوان ژورنال: THE JOURNAL OF JAPAN SOCIETY FOR CLINICAL ANESTHESIA

سال: 2019

ISSN: 0285-4945,1349-9149

DOI: 10.2199/jjsca.39.603